Radiation Physics and Engineering
A peer-reviewed journal published by K. N. Toosi University of Technology

Calculation of magnetic field effects on dose distribution, inside a heterogeneous phantom, in MR-guided helium ion-therapy using FLUKA Monte Carlo simulation code

Document Type : Research Article

Author

Nahid Hajiloo

Radiation Application Research School, Nuclear Science and Technology Research Institute, P.O. Box 31485-498, Karaj, Iran

https://doi.org/10.22034/rpe.2022.336055.1064
Abstract
In this work, the impact of magnetic field presence on the central axis depth-dose curves of helium ion beams inside a heterogeneous phantom with air and bone layers was investigated. According to the calculations, presence of the magnetic field has a considerable impact on the dose distribution of helium beams depending on the field strength and beam energy. A 32.3% abrupt increase and 92.5% reduction in dose were observed at the boundary between the water-air and the water-bone layer insert, respectively. The accuracy of the simulation was evaluated by verifying the depth dose curves of helium ion beams in a water phantom with experimental data.

Highlights

  • The perturbations caused by the presence of a magnetic  eld in the dose pro le delivered to the patient is investigated.
  • Tissue heterogeneity can cause signi cant variation in the boundary of heterogeneous layers.
  • Dose changes depends on the location of heterogeneous layers, thickness and the energy of helium ions.

Keywords

Dosimetry
Ion-therapy
Helium ions
FLUKA Code
MR-Guided therapy
Change, D. (2016). Field and wave electromagnetics, second edition. Syracuse University.
Ferrari, A., Ranft, J., Sala, P. R., et al. (2005). FLUKA: A multi-particle transport code (Program version 2005). Number CERN-2005-10. Cern.
Knausl, B., Fuchs, H., Dieckmann, K., et al. (2016). Can particle beam therapy be improved using helium ions?{a planning study focusing on pediatric patients. Acta Oncologica, 55(6):751-759.
McDonald, M. W. and Fitzek, M. M. (2010). Proton therapy. Current Problems in Cancer, 34(4):257-296.
Raaymakers, B. W., Raaijmakers, A. J., and Lagendijk, J. J. (2008). Feasibility of MRI guided proton therapy: magnetic field dose effects. Physics in Medicine & Biology, 53(20):5615.
Schardt, D., Elsasser, T., and Schulz-Ertner, D. (2010). Heavy-ion tumor therapy: Physical and radiobiological bene-fits. Reviews of Modern Physics, 82(1):383.
Sokol, O., Scifoni, E., Tinganelli, W., et al. (2017). Oxygen beams for therapy: advanced biological treatment planning and experimental veri_cation. Physics in Medicine & Biology, 62(19):7798.
Sommerer, F., Parodi, K., Ferrari, A., et al. (2006). Investigating the accuracy of the FLUKA code for transport of therapeutic ion beams in matter. Physics in Medicine & Biology, 51(17):4385.
Tessonnier, T., Mairani, A., Brons, S., et al. (2017a). Experimental dosimetric comparison of 1H, 4He, 12C and 16O scanned ion beams. Physics in Medicine & Biology, 62(10):3958.
Tessonnier, T., Mairani, A., Brons, S., et al. (2017b). Helium ions at the heidelberg ion beam therapy center: comparisons between FLUKA Monte Carlo code predictions and dosimetric measurements. Physics in Medicine & Biology, 62(16):6784.
Wilson, R. R. (1946). Radiological use of fast protons. Radiology, 47(5):487-491.
Radiation Physics and Engineering
Volume 3, Issue 1
Winter 2022
Pages 39-42

  • Receive Date 04 April 2022
  • Revise Date 20 April 2022
  • Accept Date 21 April 2022

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