Document Type: Original Article
Department of Nuclear Engineering and Physics, Amirkabir University of Technology, Tehran, Iran
Nuclear Science Research School, Nuclear Science and Technology Research Institute NSTRI, Tehran, Iran
Utilizing radioactive stents is a usual method for treatment of advanced esophageal cancer. It is necessary to investigate the dose distribution of radioactive esophageal stents before the clinical use. This study presents a dosimetric comparison between three radioactive esophageal stents: I-125 seed-loaded stent, iodine-eluting stent and double-layered iodine-eluting stent. Depth-dose and angular dose distributions were carried out using Geant4 toolkit. Moreover, the effect of interval distance between two adjacent seeds on the dose distribution was investigated. Esophageal stents loaded with I-125 seeds seems to be better than iodine-eluting stents, with the distance less than 15 mm between two adjacent seeds.
- Esophageal stents carrying I-125 seeds have shown advantages over iodine-eluting stents.
- The dose distribution of esophageal seed-loaded stents, signicantly depends on the arrangements of the seeds.
- Appropriate dose distribution was achieved for esophageal stents carrying I-125 seeds with 15 mm inter-seed spacing.