A Geant4 study on dosimetric comparison between three kinds of radioactive esophageal stents to be used in treatment of advanced esophageal cancers

Document Type: Original Article

Authors

1 Department of Nuclear Engineering and Physics‎, ‎Amirkabir University of Technology‎, ‎Tehran‎, ‎Iran

2 Nuclear Science Research School‎, ‎Nuclear Science and Technology Research Institute NSTRI‎, ‎Tehran‎, ‎Iran

Abstract

‎Utilizing radioactive stents is a usual method for treatment of advanced esophageal cancer‎. ‎It is necessary to investigate the dose distribution of radioactive esophageal stents before the clinical use‎. ‎This study presents a dosimetric comparison between three radioactive esophageal stents‎: ‎I-125 seed-loaded stent‎, ‎iodine-eluting stent and double-layered iodine-eluting stent‎. ‎Depth-dose and angular dose distributions were carried out using Geant4 toolkit‎. ‎Moreover‎, ‎the effect of interval distance between two adjacent seeds on the dose distribution was investigated‎. ‎Esophageal stents loaded with I-125 seeds seems to be better than iodine-eluting stents‎, ‎with the distance less than 15 mm between two adjacent seeds‎.

Highlights

  • Esophageal stents carrying I-125 seeds have shown advantages over iodine-eluting stents.
  • The dose distribution of esophageal seed-loaded stents, signi cantly depends on the arrangements of the seeds.
  • Appropriate dose distribution was achieved for esophageal stents carrying I-125 seeds with 15 mm inter-seed spacing.

Keywords

Radiation Physics and Engineering

Volume 1, Vol 1
Winter and Spring 2018
Pages 13-18

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History

  • Receive Date: 02 October 2017
  • Revise Date: 14 November 2017
  • Accept Date: 31 December 2017

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