18F-FDG PET/CT is commonly used for evaluation and diagnostic of many types of cancer, such as; tumor diagnosis, treatment monitoring, and radiation therapy planning. Accurate diagnostic is needed in meticulous patient preparation, including restrictions of diet and activity and management of blood glucose levels in diabetic patients, as well as an awareness of the effect of medications and environmental conditions. All of these conditions play important roles toward obtaining good-quality images, which are essential for accurate interpretation. This article introduces the new synthesis and quality control method for obtaining the best quality FDG which is used as radiopharmaceutical. All the reactions are carried out and completed in one reaction vessel without any replacement. The paper is including details of synthesis, quality control and transportation step. It is the first time that the alkaline FDG synthesis is introducing by details in Iran.
- 18F-FDG PET/CT is introduced in Iran based on news synthesis according GMP.
- It is used for diagnostic tumors, treatment monitoring and radiation therapy planning.
- The synthesis and quality control are described in details.
- It could be used as reference method for other PET centers.